Endothelial dysfunction in HIV-infected adults
This study aims to evaluate the endothelial function in HIV infected patients who have received antiretroviral therapy for at least 3 years within the PHPT cohort and analyze its relation with different markers of immune activation, inflammation and coagulation. A preliminary analysis showed that endothelial dysfunction was common in this group although all patients achieved viral suppression and were relatively young. Higher sVCAM-1 concentration was associated with higher risk of low flow-mediated dilatation (FMD).
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Than-in-at K, Phrommintikul A, Caritey B.D, Leenasirimakul P, Jaisieng N, Laomanit L, Jourdain G, Cressey T, Lallemant M, Ngo-giang-huong N, Klinbuayaem V. Endothelial dysfunction is common in HIV-infected adults with viral suppression on 5 years of ART. 11th International Congress on AIDS in Asia and the Pacific (ICAAP 11) Bangkok Thailand, November 18 -22, 2013. E-Poster.