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        • • Population pharmacokinetics of efavirenz in HIV-1 infected Thai children
        • • Efavirenz concentrations and probability of virologic failure and adverse effects in HIV-infected children
        • • Active TB in HIV-infected children
        • • Endothelial dysfunction in HIV-infected adults
        • • ​High plasma efavirenz levels and hyperlipidemia in HIV-infected children
        • • ​Incidence and risk factors of diabetes in HIV-infected adults on ART
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        • • Tolerance of zidovudine for PMTCT of HIV
        • • Timing and Risk factors of Mother to Child Transmission of HIV
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        • • Pharmacogenomics of ARVs
        • • Issues of Using Nevirapine for PMTCT
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        • การศึกษา Timing and Risk Factors of Mother to Child Transmission of HIV
        • การศึกษา Simplified Methods for ARV Measurement
        • การศึกษา Pharmacogenomics of ARVs​
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  • Symposiums
    • 2020 Mekong Hepatitis Symposium
    • August 19-20, 2019
    • September 5-7, 2018
    • November 22-24, 2017
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The article "Appointment reminders to increase uptake of HIV retesting by at-risk individuals: a randomized controlled study in Thailand" is now available online.

Download Link:
​

https://doi.org/10.1016/j.ebiom.2019.11.002


PETITE Study media (click)
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Napneung
iTAP

​2020 Mekong Hepatitis Symposium
Hepatitis B Cure and Hepatitis C Eradication (click)


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​Eve Lubin, the new Cooperation and Cultural Action Advisor ("COCAC"), Guillaume Da, the Attaché for scientific and higher education cooperation and Lisa Louveton, Project Coordinator, from the French Embassy visited Faculty of Associated Medical Sciences, Chiang Mai University on Monday 2 November 2020. They met with Prof. Sakorn Pornpraset, Dean of the Faculty of Associated Medical Sciences (AMS), Chiang Mai University (CMU), PHPT-AMS-CMU researchers and staff. The AMS-PHPT collaboration presented and they also visited the Pharmacology lab (Tim Cressey) as well as the setting for the Napneung study (Nicolas Salvadori).

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“iTAP-2 Study Co-investigators meeting” was held on Monday, 21 September 2020 at the Empress Hotel, Chiang Mai for the co-investigators from Thailand.

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Asst.Prof.Dr. Sawitree Nangola,  School of Allied Health Sciences at Phayao University submitted the project entitled “User-friendly and safe COVID-19 testing facilities in Thailand” in response to the Agence Universitaire de la Francophonie (AUF) COVID-19 international call for projects.  Her project has been selected among more than 1,500 projects and will be funded for a period of 3 months starting in June.

As part of this project and the partnership between Phayao University, Chiang Mai University and the French National Research Institute for Sustainable Development (IRD), Asst.Prof.Dr. Sawitree Nangola Dr. Eakkapote Prompunt, Dr. Chiraphat Kloypan and Ms. Thippawan Nontawong were trained from Wednesday 17 to Friday 19 June 2020 at the COVID-19 collection site at JingJai Market, Chiang Mai,  PHPT Laboratory (Nong Hoi)  and PHPT office (Kaew Nawarat) on how to collect and securely transport nasopharyngeal samples , virus detection techniques, and IT tools developed for the COVID testing project in Chiang Mai.

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Nuttada Panpradist, a Thai Ph.D. student in Bioengineering at the Department of Bioengineering, University of Washington, USA will visit PHPT on Monday, 2 March 2020 to discuss research a development of tests for HIV drug resistance and possibly for the diagnosis of other infections.

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Dr. Taraneh Shojaei, Regional Counsellor in Global Health, South-East Asia, based at the French Embassy in Thailand visited the PHPT research collaboration in Chiang Mai on Tuesday, 11 February 2020.
She met with Prof. Sakorn Pornpraset, Dean of the Faculty of Associated Medical Sciences (AMS), Chiang Mai University (CMU), researchers and staff to discuss PHPT research operations and review the status of the project “Implementation of user-friendly HIV testing and counseling services in Thailand provinces” supported by a grant from Expertise France-Initiative 5% . She also visited MAP Foundation to meet Hark Murng and discuss health issues faced by the migrant population.

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Pra-ornsuda Sukrakanchana and Gonzague Jourdain, IRD PHPT U174, visiting the DRIVE projects (ANRS12299 and ANRS 12353) implemented with Hai Phong Pharmacy and Medicine University, in Hai Phong, Vietnam on 10 December 2019. These projects aim at evaluating interventions to reduce the burden of HIV and HCV infections among intravenous drug users in Hai Phong.
Many thanks to the project team also presented DRIVE-C, a study to assess the effectiveness of a model of hepatitis C screening and integrated care, targeting people who inject drugs (NCT03537196).
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​Prof. Pan-Chyr Yang, a Professor of the Department of Internal Medicine at National Taiwan University, and Prof. Jean-Marc Egly, a member of the IRD Scientific Committee and visiting professor at National Taiwan University, visited PHPT office on Tuesday 8 October 2019. They met PHPT researchers and as well as the PHPT clinical research platform team and they also visited Faculty of Associated Medical Sciences, Chiang Mai University to meet with Prof. Sakorn Pornprasent, Dean of Faculty of Assoicated Medical Sciences, Chiang Mai University and team  for a discussion about possible collaborations between the faculty of AMS and National Taiwan University.

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at The Empress Hotel
199/42 Chang Klan Road, 
Chiang Mai, Thailand 

​The Faculty of Associated Medical Sciences, Chiang Mai University, and the international research unit 174/PHPT of the French National Research Institute for Sustainable Development (IRD) are organizing a symposium addressing ‘Elimination of Human Immunodeficiency Virus and Chronic Viral Hepatitis in South–East Asia: How close are we?”. It will be an opportunity to celebrate the 75 years of the French National Research Institute for Sustainable Development.

Infectious diseases are still a major cause of mortality and morbidity in Asia. One of the targets of the Sustainable Development Goals (SDGs) for 2030 includes the end of the HIV/AIDS epidemic and the fight against viral hepatitis. The World Health Organization has proposed targets to be reached to declare the elimination of the transmission of HIV and viral hepatitis. Even if Asia is facing a rapid rise in non-communicable diseases (diabetes, hypertension, cancer ...), several infectious diseases are still putting enormous pressure on populations and health care systems.
Diagnosis and prevention tools and even treatment already exist but are not used optimally.

However, strategies to identify those who could benefit from these treatments are yet to be defined. Despite the availability of new techniques (rapid tests, GeneXpert), the implementation of screening programs proves difficult. The "Test and Treat" strategy has emerged and now offers hope for the elimination of some chronic infections. New tools such as Pre-Exposure Prophylaxis (PrEP) are promising but remain often not accessible by those who should use them. When it comes to therapeutic strategies, the situation differs for each infection. Although there is no vaccine for hepatitis C, there are now drugs that can cure the infection. In the case of hepatitis B, there is an effective vaccine, but no treatment can cure the infection. For HIV, there is no vaccine and no cure, but treatments can efficiently control the infection. There is still a need for improvement with regard to costs, need for refinement of health policies, and reach the end for the elimination of discrimination towards infected persons.

The collaborative research program PHPT aims to develop new strategies to contribute to the elimination of infectious diseases. Current studies focus on the prevention of perinatal transmission of HBV (iTAP-1 and 2), and the early diagnosis of HIV infection in young adults in Southeast Asia (www.napneung.net).
The objectives of this symposium are:
  • To increase participants’ understanding about control, elimination and eradication as well as operational criteria to reach elimination.
  • To provide recent information about the status of the HIV and viral hepatitis epidemics in South East Asia countries in terms of evolution of incidence, prevalence, affected populations, screening strategies in place, and current action for prevention and treatment and plans for the next 10 years.
  • To present initiatives conducted to eliminate HIV, HBV or HCV transmission in the region.
During this 2-day symposium the following topics will be addressed:
  • Elimination and Eradication: Definitions and Concepts
  • Prospects for elimination
  • Non-medical factors contributing to persistence/elimination
  • Sustainable public health interventions to prevent transmission
  • “Test-and-Treat” and “Test-and-Prevent” approaches: Successes and Limitations
  • Research perspectives
 
The symposium is supported by the French National Research Institute for Sustainable Development (IRD), the French National Agency for Research on AIDS and Viral Hepatitis (ANRS), and Gilead Sciences, Inc.
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The symposium will be attended by about 120 researchers and health care professionals, practitioners from the region from Thailand, Cambodia, France, Indonesia, Lao-PDR, Malaysia, Myanmar, and Vietnam, as well as representatives of the communities affected by these diseases. Experts from the Region, USA and Europe will share their knowledge and expertise.

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Jacques Lapouge, French Ambassador in Thailand; Fabian Forni, Counsellor for Culture and Cooperation, and Thomas Baude, Honorary French Consul in Chiang Mai visited PHPT and Faculty of Associated Medical Sciences, Chiang Mai University on Friday 8 February 2019. They met Sakorn Pornprasert, Dean of the Faculty of Associated Medical Science, Chiang Mai University, Gonzague Jourdain and several researchers and staff of the PHPT-AMS research collaboration team.

​At PHPT, we design and test methods to improve the Prevention and Treatment of HIV infection and virus-associated cancers in Southeast Asia.

This is a collaboration between  Chiang Mai University  (CMU) and  Institut de Recherche p our le Développement  (IRD) for  research in  HIV/AIDS, hepatitis B (HBV), hepatitis C (HCV), human papillomavirus (HPV), and tuberculosis,  along with hospitals and other institutions in  Thailand, Laos, Cambodia, and Myanmar.

HeBOOC, a free online training course
on hepatitis B clinical management 

For the World Hepatitis Day this saturday, July 28th, the French National Research Institute for Sustainable Development (IRD) and the Chiang Mai University Faculty of Associated Medical Sciences joint research unit PHPT launch today a new tool for physicians and other health care workers to learn or update their knowledge on hepatitis B. HeBOOC is a free online self-training course available at https://www.hebooc.org/?lang=EN

HeBOOC, a free online training course on hepatitis B clinical management (English version)
File Size: 256 kb
File Type: pdf
Download File


The results of the iTAP study conducted by PHPT and its hospitals network (17 public hospitals) increase the interest for a new strategy to prevent the transmission of hepatitis B virus from mother to child. ​They have been published in the New England Journal of Medecine on March 8, 2018.

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