IRD Research Unit 174-PHPT
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The article "OLA-Simple: a software-guided HIV-1 drug resistance test for low-resource laboratories" is now available online.
Download Link:
https://doi.org/10.1016/j.ebiom.2019.11.002
The article "OLA-Simple: a software-guided HIV-1 drug resistance test for low-resource laboratories" is now available online.
Download Link:
https://doi.org/10.1016/j.ebiom.2019.11.002
Pra-ornsuda Sukrakanchana and Gonzague Jourdain, IRD PHPT U174, visiting the DRIVE projects (ANRS12299 and ANRS 12353) implemented with Hai Phong Pharmacy and Medicine University, in Hai Phong, Vietnam on 10 December 2019. These projects aim at evaluating interventions to reduce the burden of HIV and HCV infections among intravenous drug users in Hai Phong.
Many thanks to the project team also presented DRIVE-C, a study to assess the effectiveness of a model of hepatitis C screening and integrated care, targeting people who inject drugs (NCT03537196).
Many thanks to the project team also presented DRIVE-C, a study to assess the effectiveness of a model of hepatitis C screening and integrated care, targeting people who inject drugs (NCT03537196).
Prof. Pan-Chyr Yang, a Professor of the Department of Internal Medicine at National Taiwan University, and Prof. Jean-Marc Egly, a member of the IRD Scientific Committee and visiting professor at National Taiwan University, visited PHPT office on Tuesday 8 October 2019. They met PHPT researchers and as well as the PHPT clinical research platform team and they also visited Faculty of Associated Medical Sciences, Chiang Mai University to meet with Prof. Sakorn Pornprasent, Dean of Faculty of Assoicated Medical Sciences, Chiang Mai University and team for a discussion about possible collaborations between the faculty of AMS and National Taiwan University.
at The Empress Hotel
199/42 Chang Klan Road,
Chiang Mai, Thailand
199/42 Chang Klan Road,
Chiang Mai, Thailand
Download the Agenda
The Faculty of Associated Medical Sciences, Chiang Mai University, and the international research unit 174/PHPT of the French National Research Institute for Sustainable Development (IRD) are organizing a symposium addressing ‘Elimination of Human Immunodeficiency Virus and Chronic Viral Hepatitis in South–East Asia: How close are we?”. It will be an opportunity to celebrate the 75 years of the French National Research Institute for Sustainable Development.
Infectious diseases are still a major cause of mortality and morbidity in Asia. One of the targets of the Sustainable Development Goals (SDGs) for 2030 includes the end of the HIV/AIDS epidemic and the fight against viral hepatitis. The World Health Organization has proposed targets to be reached to declare the elimination of the transmission of HIV and viral hepatitis. Even if Asia is facing a rapid rise in non-communicable diseases (diabetes, hypertension, cancer ...), several infectious diseases are still putting enormous pressure on populations and health care systems.
Diagnosis and prevention tools and even treatment already exist but are not used optimally.
However, strategies to identify those who could benefit from these treatments are yet to be defined. Despite the availability of new techniques (rapid tests, GeneXpert), the implementation of screening programs proves difficult. The "Test and Treat" strategy has emerged and now offers hope for the elimination of some chronic infections. New tools such as Pre-Exposure Prophylaxis (PrEP) are promising but remain often not accessible by those who should use them. When it comes to therapeutic strategies, the situation differs for each infection. Although there is no vaccine for hepatitis C, there are now drugs that can cure the infection. In the case of hepatitis B, there is an effective vaccine, but no treatment can cure the infection. For HIV, there is no vaccine and no cure, but treatments can efficiently control the infection. There is still a need for improvement with regard to costs, need for refinement of health policies, and reach the end for the elimination of discrimination towards infected persons.
The collaborative research program PHPT aims to develop new strategies to contribute to the elimination of infectious diseases. Current studies focus on the prevention of perinatal transmission of HBV (iTAP-1 and 2), and the early diagnosis of HIV infection in young adults in Southeast Asia (www.napneung.net).
The objectives of this symposium are:
The symposium is supported by the French National Research Institute for Sustainable Development (IRD), the French National Agency for Research on AIDS and Viral Hepatitis (ANRS), and Gilead Sciences, Inc.
The symposium will be attended by about 120 researchers and health care professionals, practitioners from the region from Thailand, Cambodia, France, Indonesia, Lao-PDR, Malaysia, Myanmar, and Vietnam, as well as representatives of the communities affected by these diseases. Experts from the Region, USA and Europe will share their knowledge and expertise.
Infectious diseases are still a major cause of mortality and morbidity in Asia. One of the targets of the Sustainable Development Goals (SDGs) for 2030 includes the end of the HIV/AIDS epidemic and the fight against viral hepatitis. The World Health Organization has proposed targets to be reached to declare the elimination of the transmission of HIV and viral hepatitis. Even if Asia is facing a rapid rise in non-communicable diseases (diabetes, hypertension, cancer ...), several infectious diseases are still putting enormous pressure on populations and health care systems.
Diagnosis and prevention tools and even treatment already exist but are not used optimally.
However, strategies to identify those who could benefit from these treatments are yet to be defined. Despite the availability of new techniques (rapid tests, GeneXpert), the implementation of screening programs proves difficult. The "Test and Treat" strategy has emerged and now offers hope for the elimination of some chronic infections. New tools such as Pre-Exposure Prophylaxis (PrEP) are promising but remain often not accessible by those who should use them. When it comes to therapeutic strategies, the situation differs for each infection. Although there is no vaccine for hepatitis C, there are now drugs that can cure the infection. In the case of hepatitis B, there is an effective vaccine, but no treatment can cure the infection. For HIV, there is no vaccine and no cure, but treatments can efficiently control the infection. There is still a need for improvement with regard to costs, need for refinement of health policies, and reach the end for the elimination of discrimination towards infected persons.
The collaborative research program PHPT aims to develop new strategies to contribute to the elimination of infectious diseases. Current studies focus on the prevention of perinatal transmission of HBV (iTAP-1 and 2), and the early diagnosis of HIV infection in young adults in Southeast Asia (www.napneung.net).
The objectives of this symposium are:
- To increase participants’ understanding about control, elimination and eradication as well as operational criteria to reach elimination.
- To provide recent information about the status of the HIV and viral hepatitis epidemics in South East Asia countries in terms of evolution of incidence, prevalence, affected populations, screening strategies in place, and current action for prevention and treatment and plans for the next 10 years.
- To present initiatives conducted to eliminate HIV, HBV or HCV transmission in the region.
- Elimination and Eradication: Definitions and Concepts
- Prospects for elimination
- Non-medical factors contributing to persistence/elimination
- Sustainable public health interventions to prevent transmission
- “Test-and-Treat” and “Test-and-Prevent” approaches: Successes and Limitations
- Research perspectives
The symposium is supported by the French National Research Institute for Sustainable Development (IRD), the French National Agency for Research on AIDS and Viral Hepatitis (ANRS), and Gilead Sciences, Inc.
The symposium will be attended by about 120 researchers and health care professionals, practitioners from the region from Thailand, Cambodia, France, Indonesia, Lao-PDR, Malaysia, Myanmar, and Vietnam, as well as representatives of the communities affected by these diseases. Experts from the Region, USA and Europe will share their knowledge and expertise.
AMS-PHPT meeting on Thursday 20 June 2019 at the Faculty of Associated Medical Sciences
(meeting room 1, floor 1, building 2): Drs. Gonzague Jourdain, Nicole Ngo-Giang-Huong, Sophie Le Coeur, Luc Decker and Tim Cressey reviewed with Prof. Sakorn Pornpasert; Dean of Faculty of Associated Medical Sciences (AMS), Chiang Mai University (CMU) and other faculties and researchers of the Faculty the main current studies as well as well as projects carried out under the AMS-PHPT collaboration.They also discussed possible future joint research projects.
(meeting room 1, floor 1, building 2): Drs. Gonzague Jourdain, Nicole Ngo-Giang-Huong, Sophie Le Coeur, Luc Decker and Tim Cressey reviewed with Prof. Sakorn Pornpasert; Dean of Faculty of Associated Medical Sciences (AMS), Chiang Mai University (CMU) and other faculties and researchers of the Faculty the main current studies as well as well as projects carried out under the AMS-PHPT collaboration.They also discussed possible future joint research projects.
Prof. Jean-Marc Egly, Director Emeritus of Research at INSERM, a member of the French Academy of Sciences, and a member of the Scientific Committee of the French National Research Institute for Sustainable Development (IRD) and Prof. Tang-Long Shen, Vice-Dean, Department of Plant Pathology and Microbiology, National Taiwan University visited PHPT office and laboratory on Wednesday 22 May 2019 for a presentation of current activities.
They met PHPT researchers as well as the PHPT clinical research platform team, and discuss the possibility to set up an advisory scientific program review with researchers from the region to help set up future orientations for the research group.Many thanks for their visit and great advices!
The PHPT team looks forward for this review, tentatively planned in Fall 2019.
They met PHPT researchers as well as the PHPT clinical research platform team, and discuss the possibility to set up an advisory scientific program review with researchers from the region to help set up future orientations for the research group.Many thanks for their visit and great advices!
The PHPT team looks forward for this review, tentatively planned in Fall 2019.
Jacques Lapouge, French Ambassador in Thailand; Fabian Forni, Counsellor for Culture and Cooperation, and Thomas Baude, Honorary French Consul in Chiang Mai visited PHPT and Faculty of Associated Medical Sciences, Chiang Mai University on Friday 8 February 2019. They met Sakorn Pornprasert, Dean of the Faculty of Associated Medical Science, Chiang Mai University, Gonzague Jourdain and several researchers and staff of the PHPT-AMS research collaboration team.
Jean-Paul Moatti, President-Director General, IRD, France; Jacques Berger, IRD Representative in Thailand; Olivier Evrard, future IRD Representative in Thailand, and Nejma André, in charge of Asia-Pacific affairs at IRD, visited PHPT and Faculty of Associated Medical Science, Chiang Mai University on Saturday and Sunday 19-20 January 2019. They met Sakorn Pornprasert, Dean of the Faculty of Associated Medical Science, Chiang Mai University, Gonzague Jourdain and several researchers and staff of the PHPT research collaboration team, on Saturday; and Chayan Vaddhanaphuti at the Faculty of Social Sciences, Chiang Mai University on Sunday. On Thursday 24 January, JP Moatti, N André, Eric Deharo and others scientists visited Mother and Newborn Hospital in Vientiane, Lao PDR with Gonzague Jourdain who presented the iTAP-2 study in the presence of the Director of the hospital and Touy Chanthalansy, principal site investigator.
A workshop was organized on December 17, 2018, at Mae Fah Luang University, Chiang Rai to discuss preliminary results of the Napneung Project
Napneung (www.napneung.net) is project where anybody can be tested for HIV, syphilis, hepatitis B and C, free of charge. The research team is studying methods to increase access to testing and retesting for perons at high risk of infection.
The French Ambassador to Thailand Jacques Lapouge, Associate Prof. Dr. Vanchai Sirichana, President of Mae Fah Luang University, and Assistant Prof. Dr. Wasna Sirirungsi, former dean of the faculty of Associated Medical Sciences, Chiang Mai University, gave opening remarks.
Napneung (www.napneung.net) is project where anybody can be tested for HIV, syphilis, hepatitis B and C, free of charge. The research team is studying methods to increase access to testing and retesting for perons at high risk of infection.
The French Ambassador to Thailand Jacques Lapouge, Associate Prof. Dr. Vanchai Sirichana, President of Mae Fah Luang University, and Assistant Prof. Dr. Wasna Sirirungsi, former dean of the faculty of Associated Medical Sciences, Chiang Mai University, gave opening remarks.
At PHPT, we design and test methods to improve the Prevention and Treatment of HIV infection and virus-associated cancers in Southeast Asia.
This is a collaboration between Chiang Mai University (CMU) and Institut de Recherche p our le Développement (IRD) for research in HIV/AIDS, hepatitis B (HBV), hepatitis C (HCV), human papillomavirus (HPV), and tuberculosis, along with hospitals and other institutions in Thailand, Laos, Cambodia, and Myanmar.
This is a collaboration between Chiang Mai University (CMU) and Institut de Recherche p our le Développement (IRD) for research in HIV/AIDS, hepatitis B (HBV), hepatitis C (HCV), human papillomavirus (HPV), and tuberculosis, along with hospitals and other institutions in Thailand, Laos, Cambodia, and Myanmar.
HeBOOC, a free online training course
on hepatitis B clinical management
For the World Hepatitis Day this saturday, July 28th, the French National Research Institute for Sustainable Development (IRD) and the Chiang Mai University Faculty of Associated Medical Sciences joint research unit PHPT launch today a new tool for physicians and other health care workers to learn or update their knowledge on hepatitis B. HeBOOC is a free online self-training course available at https://www.hebooc.org/?lang=EN
| HeBOOC, a free online training course on hepatitis B clinical management (English version) |
The results of the iTAP study conducted by PHPT and its hospitals network (17 public hospitals) increase the interest for a new strategy to prevent the transmission of hepatitis B virus from mother to child. They have been published in the New England Journal of Medecine on March 8, 2018.
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